Joost G J Hoenderop Selected Research

Intestinal Hypomagnesemia 1

1/2011	Transient receptor potential melastatin 6 knockout mice are lethal whereas heterozygous deletion results in mild hypomagnesemia.
8/2009	The role of transient receptor potential channels in kidney disease.
8/2007	TRP channels in kidney disease.
1/2004	TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.

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Joost G J Hoenderop Research Topics

Disease

11	Chronic Renal Insufficiency 02/2024 - 12/2012
10	Kidney Diseases (Kidney Disease) 01/2024 - 08/2009
9	Hypercalciuria 01/2013 - 12/2003
8	Type 2 Diabetes Mellitus (MODY) 01/2024 - 01/2017
7	Vascular Calcification 04/2024 - 01/2018
6	Autosomal Dominant Polycystic Kidney (ADPKD) 04/2024 - 08/2009
5	Hypocalcemia 04/2024 - 07/2003
5	Cysts 02/2023 - 10/2013
5	Seizures (Absence Seizure) 01/2023 - 07/2012
5	Proteinuria 04/2016 - 10/2011
5	Rickets (Rachitis) 08/2009 - 09/2002
4	Renal Insufficiency (Renal Failure) 02/2024 - 09/2004
4	Hypokalemia 02/2023 - 08/2013
4	Hypertension (High Blood Pressure) 01/2019 - 12/2013
4	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 07/2013 - 08/2007
4	Bone Resorption 01/2013 - 11/2005
4	Intestinal Hypomagnesemia 1 01/2011 - 01/2004
3	Mason-Type Diabetes 02/2023 - 01/2018
3	Inflammation (Inflammations) 01/2022 - 06/2008
3	Insulin Resistance 01/2022 - 01/2016
3	Gitelman Syndrome 12/2016 - 09/2004
3	Secondary Hyperparathyroidism 12/2012 - 02/2004
2	Neoplasms (Cancer) 01/2022 - 05/2016
2	Heart Failure 01/2021 - 06/2014
2	Hyperaldosteronism (Conn Syndrome) 01/2021 - 01/2021
2	Intellectual Disability (Idiocy) 01/2021 - 01/2021
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2020 - 08/2007
2	Body Weight (Weight, Body) 01/2019 - 04/2013
2	Angelman Syndrome (Syndrome, Angelman) 01/2018 - 03/2011
2	Uremia 06/2015 - 12/2013
2	Diabetes Mellitus 01/2015 - 08/2007
2	Williams Syndrome (Williams-Beuren Syndrome) 07/2014 - 11/2010
2	Acidosis 12/2013 - 03/2006
2	Alkalosis 03/2006 - 09/2004
2	Vitamin D Deficiency 02/2004 - 07/2003
2	Hyperparathyroidism 07/2003 - 09/2002
1	Hypoparathyroidism 01/2023
1	Muscle Cramp (Cramp) 01/2023
1	Type 1 Kenny-Caffey syndrome 01/2023
1	Spasm (Spasms) 01/2023
1	Hypertrophy 01/2022
1	Hyperuricemia 01/2022
1	Kidney Neoplasms (Kidney Cancer) 07/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021

Drug/Important Bio-Agent (IBA)

19	MagnesiumIBA 04/2024 - 05/2007
10	ElectrolytesIBA 04/2024 - 04/2013
10	Proteins (Proteins, Gene)FDA Link 01/2023 - 03/2004
10	Vitamin D FDA LinkGeneric 04/2016 - 07/2003
7	CalciumIBA 04/2024 - 07/2007
6	Calcitriol (Calcijex)FDA LinkGeneric 12/2015 - 09/2002
6	TRPC6 Cation ChannelIBA 06/2014 - 08/2007
5	MineralsIBA 02/2024 - 03/2004
5	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2020
5	Transcription Factors (Transcription Factor)IBA 02/2023 - 01/2010
5	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2016
4	Adenosine Triphosphate (ATP)IBA 04/2024 - 01/2020
4	Parathyroid Hormone (Parathormone)IBA 01/2023 - 10/2005
4	AldosteroneIBA 01/2021 - 09/2004
4	Messenger RNA (mRNA)IBA 01/2019 - 03/2006
4	ThiazidesIBA 12/2016 - 09/2004
4	Carrier Proteins (Binding Protein)IBA 10/2006 - 02/2004
3	Phosphates (Orthophosphate)IBA 02/2024 - 01/2020
3	Hepatocyte Nuclear FactorsIBA 02/2023 - 10/2013
3	Hepatocyte Nuclear Factor 1IBA 01/2023 - 01/2010
3	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2015 - 10/2011
3	Transient Receptor Potential ChannelsIBA 03/2011 - 06/2005
2	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 04/2024 - 01/2023
2	CreatinineIBA 02/2024 - 04/2013
2	Hemoglobins (Hemoglobin)IBA 01/2021 - 01/2015
2	CyclinsIBA 01/2021 - 01/2021
2	ReninIBA 01/2021 - 12/2013
2	Fibroblast Growth Factor-23IBA 01/2020 - 04/2016
2	Triglycerides (Triacylglycerol)IBA 01/2019 - 01/2017
2	Blood Glucose (Blood Sugar)IBA 01/2019 - 01/2015
2	SaltsIBA 01/2018 - 12/2016
2	CytokinesIBA 06/2015 - 07/2002
2	Adenosine Triphosphatases (ATPase)IBA 06/2015 - 01/2010
2	Proton Pump InhibitorsIBA 01/2015 - 07/2012
2	Peptide Hydrolases (Proteases)FDA Link 01/2015 - 11/2012
2	Diphosphonates (Bisphosphonates)IBA 07/2014 - 11/2008
2	CationsIBA 12/2013 - 01/2004
2	1,25-dihydroxyvitamin DIBA 01/2013 - 06/2008
2	ErbB Receptors (EGF Receptor)IBA 07/2012 - 05/2007
2	DiureticsIBA 07/2012 - 08/2007
2	Immunosuppressive Agents (Immunosuppressants)IBA 08/2007 - 03/2004
2	Tissue Kallikreins (Tissue Kallikrein)IBA 07/2007 - 10/2006
1	Urea (Carbamide)FDA LinkGeneric 02/2024
1	calcium hydroxide drug combination barium sulfateIBA 01/2023
1	Phosphotransferases (Kinase)IBA 01/2023
1	matrigelIBA 01/2023
1	calcium phosphateIBA 01/2023
1	Colloids (Colloid)IBA 01/2023
1	NucleotidesIBA 01/2023
1	CeramidesIBA 01/2022
1	Purinergic Receptors (Receptors, Purine)IBA 01/2022
1	Insulin (Novolin)FDA Link 01/2022
1	IsotopesIBA 07/2021

Therapy/Procedure

2	Glycemic Control 01/2021 - 01/2019
2	Therapeutics 06/2020 - 02/2012
1	Nephrectomy 01/2022